Past Master’s Theses

Topics of master’s theses completed at the Department of Embryology

2025

Kacper Smoliński: The role of the PIEZO1 protein in the preimplantation development of mouse embryos

2024

Kamila Lech: Influence of activin A on regulative abilities of preimplantation mouse embryo
Izabela Wysocka: Potential of embryos deprived of activin A (InhbaKO/KO) to form a functional trophectoderm
Alicja Rak: Cytoplasmic movement velocity as a marker of mouse oocyte quality
Anna Gałązkiewicz: At what stage of development does the regulation of cell number occur in mouse chimeric embryos?
Agata Lewandowska: Determination of the effect of heme oxygenase 1 expression and activity on paclitaxel and carboplatin toxicity in ovarian cancer cell lines

2023

Anna Szpakowska: The role of activin A in derivation, maintenance of pluripotency and differentiation of mouse embryonic stem cells
Iga Pilaszek: Assessment of cytoplasmic velocity in mouse embryos as a tool for evaluating their implantation competence

2022

Marta Żbikowska: The role of activin A in the plasticity of preimplantation mouse embryos
Zuzanna Machniewska: Dynamics of cytoplasmic movement in zygotes as a predictor of the developmental potential of mammalian embryos
Alicja Stodulska: The influence of bisphenol A on mitochondrial activity and amount of reactive oxygen species in mouse oocytes maturing in vitro
Zuzanna Gronek: Bisphenol A and its effect on histone H3 methylation in mouse oocytes
Magdalena Oślislok: When does cell number regulation occur in the post-implantation development of chimeric mouse embryos?

2021

Barbara Bubacz: The role of microRNA 322 and 106a in differentiation of trophectoderm and primitive endoderm cell lineages in preimplantation murine embryo
Magdalena Najechalska: Effect of bisphenol A on meiotic maturation of mouse oocytes and their ability to generate Ca2+ oscillations in response to fertilization
Katarzyna Sałas: Assessment of transport efficiency between granulosa cells and GV oocytes of distinct transcriptional status

2020

Zuzanna Kopeć: The role of Na+/K+-ATPase and Na+/H+ exchanger in the preimplantation development of a mouse embryo
Julia Michalkiewicz: The role of histone H3 lysine 9 dimethylation in S phase termination and organization of mitotic spindle in mouse zygote
Eliza Winek: The role of miR-93 and miR-125a in the differentiation of trophectoderm and primitive endoderm cell lineages in the preimplantation mouse embryo
Alicja Gross: The role of apoptosis in the plasticity of preimplantation mouse embryos
Aleksandra Sobkowiak: Optical Coherence Microscopy as a tool for mouse embryo quality assessment

2019

Ewa Kosyl: Do the twin blastocysts obtained from single blastomeres of the 4-cell mouse embryo differ in their ability to create precursors of epiblast and primitive endoderm?
Katarzyna Wołukanis: The FGF4/ERK pathway’s role in regulation of preimplantation mouse embryo development

2018

Alicja Przychodzka: Impact of sirtuins on [Ca2+]i oscillations in fertilized postovulatory aged mouse oocytes

2017

Monika Fluks: Different regulation of Ca2+ homeostasis in oocytes and embryos derived from GV oocytes with distinct transcriptional status
Aleksandra Pompa: Analysis of the selected H3 histone modifications in the maturing Djungarian hamster oocytes and mouse-hamster hybrid zygotes
Katarzyna Krysztofiak: The role of histone H3 serine 10 phosphorylation in the organization of heterochromatin during early preimplantation development of mouse embryo

2016

Karolina Rogala: Acentriolar spindle assembly in anucleate halves obtained from primary mouse oocytes
Agnieszka Kiełbasa: Effect of aging and the associated oxidative stress on regulation of Ca2+ oscillations in mouse oocytes
Michał Brouze: Effect of postovulatory ageing on the first cell cycle in a mouse embryo
Patrycja Strączyńska: Impact of a postovulatory aging on selected aspects of the mitochondrial functionality in mouse oocytes
Maria Guzewska: Differentiation of ICM cells in embryos, to which ES cells were injected at 8-cell – stage
Katarzyna Wilczak: Regulative capacity of chimeric mouse embryos created by aggregation of components differing in the developmental stage

2015

Anna Małgorzata Stachowiak: Localization of cells originating from blastomeres that did not polarize at 8-cell stage. A study on mice chimera embryos
Katarzyna Prokurat: Effects of postovulatory aging and various culture conditions on mouse preimplantation embryo morphokinetics

2014

Katarzyna Natalia Klimczewska: Role of aPKCζ in inhibiting Hippo pathway in precursor cells of trophectoderm in the preimplantation mouse embryo
Dorota Sabat: The impact of postovulatory aging and the associated oxidative stress on mouse oocytes and developmental potential of the obtained embryos
Marcin Szpila: Effects of postovulatory aging on developmental competence of mouse oocytes
Błażej Krupa: Role of E-cadherin in the formation of primitive endoderm in the mouse embryo
Monika Humięcka: Embryonic development of mice generated by microinjection of mouse embryonic stem cells into 8-cell stage mouse embryo
Monika Piołun-Noyszewska: The role of intercellular interactions involving Fgf4/MAPK signaling pathway in the differentiation of embryonic stem cells and mouse embryonic cells

2013

Anna Lenkiewicz: Occurrence and localization of Orc2 protein in 1-4-cell mouse embryo
Katarzyna Czajkowska: The Orc2 protein in maturing mouse oocytes: relations to the microtubular cytoskeleton and possible function
Katarzyna Świtoń: Inner cell mass of the mouse blastocyst: cell fate vs cell plasticity
Dawid Wolaniuk: Unrelated to DNA replication functions of Cdc6 during maturation of mouse oocyte

2012

Michał Pasternak: The role of histone H3 serine 10 phosphorylation during preimplantation development of mouse embryo
Karolina Jodkowska: Generation of intraspecific (mouse<->mouse) and interspecific (mouse<->rat) chimaeras from mouse embryonic stem cells and mouse or rat early cleavage embryos
Ewa Mazur: Fate of primary and secondary inner cells in preimplantation mouse embryo
Karolina Buka: Generation of intraspecific (mouse<->mouse) and interspecific (mouse<->rat) chimaeras from mouse embryonic stem cells and mouse or rat early cleavage embryos

2011

Joanna Jachowicz: The presence and function of Cdc6 protein during meiotic maturation of mouse oocytes
Magdalena Krupa: Determination of cell fate in mouse preimplantation development

2010

Aleksandra Flaht: Expression of Cdx2 transcription factor in mouse embryos after ECCD-1 – induced decompaction of blastomeres at the 8-16 – cell stage
Małgorzata Łuksza: Cytogenetic analysis of human sperm chromosomes after intracytoplasmic injection into mouse oocyte

2009

Katarzyna Filimonow: Obtaining transgenic mouse with tetracyclin reversed transactivatr under control of the EF1alfa promotor
Marta Teperek: Influence of histone H3 serine 10 phosphorylation on the course of I and II cell cycle of the cleaving mouse embryo
Ilona Kondratiuk: Appearance of Cdx2 protein in isolated blastomeres of mouse embryos
Łukasz Stańczuk: Are ICM cells of murine embryo able to differentiate into trophectoderm cells?
Magdalena Januszewska: Influence of curcumin on the maturation of mouse oocytes. Phosphorylation of histone H2AX in mouse oocytes
Katarzyna Bazydło: Effect of the compaction on Cdx2 protein expression in isolated mouse embryo blastomers
Małgorzata Łuksza: Cytogenetic analysis of human sperm chromosomes after intracytoplasmic injection into mouse oocyte

2008

Iwona Wewiór: Expression of Cdx2 transcription factor in the preimplantation mouse embryo after induction of premature compaction and after reversal of compaction
Eliza Żyłkiewicz: Role of the CD9 protein in establishment of the membrane block to polyspermy; an ultrastructural study
Tomasz Grygorowicz: Phosphorylation of histone H3 serine 10 in the male chromatin of parthenogenetic mouse embryos, inseminated at different times after activation

2007

Zuzanna Maria Maciejewska: Regulation of the first mitosis of F1 (C57Bl/6 x CBA/H) and LT/Sv mouse embryos. Involvement of ERK1/2 and ERK5 MAP kinase pathways
Karolina Kozdrój: Role of cysteine-proteases in male chromatin remodeling after fertilization and in preimplantation embryonic development in mice
Małgorzata Wierzbicka: Histone H3 phosphorylation at serine 10 during meiotic maturation and after fertilization of maturing and ovulated mouse oocytes
Krystyna Żyżyńska: The order of cleavage of the first two blastomeres and the origin of cells surrounding the nascent blastocoele in mouse embryos

2006

Maciej Meglicki: Acetylation and methylation of histone H3 and localization of HP1a protein during oogenesis and in the one-cell mouse embryo
Agnieszka Jędrusik: Mouse oocyte fertilised during in vitro maturation can be activated by insemination in metaphase II